Endoscopic Clips Market to Surge, Expected to Reach USD 849.9 Million by 2033

Trishita Deb
Trishita Deb

Updated · Apr 29, 2025

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Overview

New York, NY – April 29, 2025 – The Global Endoscopic Clips Market size is expected to be worth around USD 849.9 Million by 2033 from USD 420.1 Million in 2023, growing at a CAGR of 7.3% during the forecast period from 2024 to 2033.

Endoscopic clips are small, mechanical devices used during endoscopic procedures to close gastrointestinal perforations, control bleeding, and secure tissue. These clips are deployed through an endoscope, allowing minimally invasive treatment without the need for open surgery. Their usage has become a standard practice in therapeutic endoscopy, contributing significantly to improved patient outcomes and faster recovery times.

The growth of the endoscopic clips market can be attributed to the rising prevalence of gastrointestinal diseases, the increasing adoption of minimally invasive surgeries, and advancements in endoscopic technologies. The clips are primarily used in procedures such as polypectomy, mucosal resection, and the management of gastrointestinal bleeding. Modern clips offer enhanced rotational control, improved closure strength, and the ability to be repositioned before deployment, offering greater procedural flexibility to physicians.

Regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA), have approved a range of endoscopic clips, reflecting their safety and efficacy profiles. Hospitals, ambulatory surgical centers, and specialty clinics are the primary end-users driving demand. As healthcare providers emphasize patient safety and procedure efficiency, the adoption of endoscopic clips is expected to witness steady growth globally, supported by technological innovation and expanding clinical applications.

Endoscopic Clips Market Size

Key Takeaways

  • Market Size: The Global Endoscopic Clips Market is projected to reach approximately USD 849.9 million by 2033, growing from USD 420.1 million in 2023.
  • Market Growth: The market is anticipated to expand at a compound annual growth rate (CAGR) of 7.3% during the forecast period from 2024 to 2033.
  • Application Analysis: In 2023, the Hemostasis segment led the market, accounting for 58.1% of the total application share globally.
  • End-Use Analysis: Hospitals dominated the end-user segment in 2023, capturing 51.6% of the total revenue share.
  • Regional Analysis: North America retained its leading position in the global endoscopic clips market, securing over 37.8% of the overall revenue.
  • Technological Advancements: Continuous innovations in endoscopic clip design and deployment techniques are improving procedural efficiency and enhancing patient outcomes.
  • Expanding Applications: The clinical use of endoscopic clips is increasing across multiple areas, including hemostasis, tissue closure, and lesion marking during endoscopic procedures.
  • Healthcare Expenditure: Rising investments in healthcare infrastructure and service quality are contributing to the sustained growth of the endoscopic clips market.
  • Patient Preference: A growing preference for minimally invasive treatment options among patients is driving the wider adoption of endoscopic clips in therapeutic procedures.

Segmentation Analysis

Application Analysis: The Endoscopic Clips market is primarily segmented into Endoscopic Marking, Hemostasis, and others. Hemostasis led the market in 2023 with a 58.1% share, driven by its key role in controlling bleeding during gastrointestinal procedures. The high prevalence of gastrointestinal bleeding disorders and the proven efficacy of endoscopic clips in managing such conditions have significantly contributed to this dominance. Upper gastrointestinal bleeding (UGIB), affecting 80 to 150 individuals per 100,000 annually, further supports the growth of this segment.

End-User Analysis: The Endoscopic Clips market is categorized into hospitals, Ambulatory Surgical Centers (ASCs), and others. In 2023, hospitals dominated the market with a 51.6% revenue share, owing to their comprehensive healthcare services, advanced medical equipment, and capability to perform complex endoscopic procedures. Hospitals also benefit from specialized staff and emergency management capabilities. However, ASCs are projected to experience the highest CAGR during 2024-2033, due to their cost-effectiveness and the convenience of outpatient procedures that offer shorter recovery times and reduced hospital stays.

Market Segments

By Application

  • Endoscopic Marking
  • Hemostasis
    • Mucosal/Submucosal Defects
    • Bleeding Ulcers
    • Bleeding Arteries
    • Polypectomy Sites
  • Others

By End-User

  • Hospitals
  • Ambulatory Surgical Centers
  • Specialty Clinics
  • Others

Regional Analysis

In 2023, North America led the Endoscopic Clips market, capturing 37.8% of the revenue share. The region’s dominance is driven by the high prevalence of gastrointestinal disorders, a robust healthcare infrastructure, and significant investments in medical technology. North America also benefits from a large pool of skilled healthcare professionals and the presence of key industry players, including Cook Medical and Boston Scientific Corporation, who are leading innovation in the endoscopic market.

The growing emphasis on minimally invasive surgeries, coupled with the rising geriatric population, further fuels the demand for endoscopic clips in the region. According to the U.S. Census Bureau, the population aged 65 and older is expected to reach 94.7 million by 2060, a significant portion of which will require endoscopic procedures. Additionally, favorable reimbursement policies and advanced healthcare facilities support the widespread adoption of endoscopic interventions in North America.

Emerging Trends

Advancements in Clip Design and Materials: Recent developments have focused on enhancing the mechanical properties of endoscopic clips. Innovations include the use of shape-memory alloys like nitinol, which provide superelasticity and allow for better tissue approximation. Some clips now feature multiple anchoring tips and adjustable spans up to 16 mm, enabling more secure and versatile applications.

Expansion of Clinical Indications

  • Closing mucosal defects post-endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD).
    Securing feeding tubes to the intestinal wall.
  • Affixing self-expanding metal stents in the esophagus.
  • Marking lesions for surgical navigation.

Integration with Advanced Endoscopic Techniques: The combination of endoscopic clips with other modalities, such as over-the-scope clip (OTSC) systems, has improved the management of complex GI lesions, including large perforations and fistulas. These integrated approaches enhance the therapeutic capabilities of endoscopy.

Use Cases

Management of Gastrointestinal Bleeding

  • Peptic Ulcers: Clips can arrest active bleeding by mechanically compressing the bleeding vessel.
  • Mallory-Weiss Tears: Superficial mucosal lacerations at the gastroesophageal junction are effectively treated with clips.

Dieulafoy’s Lesions: These aberrant submucosal vessels can be managed by clip application to prevent hemorrhage.

Closure of Perforations and Fistulas: In cases of iatrogenic perforations during endoscopic procedures or spontaneous GI tract fistulas, clips provide a non-surgical method for closure, reducing the need for open surgical interventions.

Post-Polypectomy Bleeding Prevention: Applying clips prophylactically after polypectomy, especially for large or sessile polyps, can minimize the risk of delayed bleeding, enhancing patient safety.

Securing Medical Devices: Clips assist in anchoring devices such as feeding tubes or stents within the GI tract, ensuring their proper placement and function.

Conclusion

In conclusion, the Endoscopic Clips market is poised for significant growth, driven by the increasing prevalence of gastrointestinal disorders, advancements in minimally invasive surgery, and continuous technological innovations. The market is projected to reach USD 849.9 million by 2033, with hemostasis applications leading the demand.

Hospitals continue to dominate as the primary end-users, while Ambulatory Surgical Centers are set to experience the highest growth. As the adoption of endoscopic clips expands across diverse clinical applications, including gastrointestinal bleeding management and mucosal defect closure, the market is expected to continue evolving with improved clip designs and integration with advanced endoscopic techniques.

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Trishita Deb

Trishita Deb

Trishita has more than 8+ years of experience in market research and consulting industry. She has worked in various domains including healthcare, consumer goods, and materials. Her expertise lies majorly in healthcare and has worked on more than 400 healthcare reports throughout her career.

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