Table of Contents
Overview
New York, NY – May 07, 2025 – Global Biopreservation Market size is expected to be worth around USD 35.3 billion by 2033 from USD 2.9 billion in 2023, growing at a CAGR of 28.4% during the forecast period 2024 to 2033
Biopreservation is a critical process in modern biotechnology and healthcare that involves preserving the integrity of biological samples such as cells, tissues, and organs. This method ensures that biological materials remain viable for extended periods, supporting applications in regenerative medicine, biobanking, and advanced therapies.
At its core, biopreservation relies on low-temperature storage, often using cryopreservation techniques where samples are maintained in liquid nitrogen at temperatures as low as -196°C. In addition to temperature control, cryoprotective agents (CPAs) are used to prevent ice crystal formation that can damage cellular structures.
The technology plays a vital role in organ transplantation, stem cell therapy, reproductive health (such as sperm and egg banking), and the storage of vaccines and biological research samples. With the rising demand for personalized medicine and cell-based therapies, the need for reliable biopreservation methods has grown significantly.
Global health initiatives and advances in cold chain logistics have further accelerated the adoption of biopreservation systems. Automation, smart freezers, and real-time monitoring tools are being increasingly integrated to improve sample traceability and quality control. As the life sciences industry expands, biopreservation remains a foundational element, ensuring the long-term usability and safety of biological materials critical to research, diagnostics, and therapeutic interventions.
Key Takeaways
- Market size: The Global Biopreservation Market is projected to grow significantly, reaching a valuation of approximately USD 35.3 billion by 2033, rising from USD 2.9 billion in 2023. This expansion reflects a strong compound annual growth rate (CAGR) of 28.4% during the forecast period from 2024 to 2033.
- Product Segmentation: In 2023, the equipment segment emerged as the leading category, accounting for 44.4% of the total market share. The demand is driven by the increasing use of advanced preservation systems and storage solutions.
- Application Insights: Biobanking was the dominant application area, capturing 50.0% of the market in 2023. The growing emphasis on personalized medicine and large-scale biological sample storage continues to drive this segment.
- Cell Provider Segment: The tumor cells segment recorded a remarkable performance, contributing 38.5% of market revenue in 2023. This growth is attributed to rising research in oncology and the demand for preserved cancer cell lines.
- Regional Highlights: North America led the global market with a revenue share of 42.2% in 2023, supported by advanced healthcare infrastructure and increased R\&D funding.
- Regulatory and R\&D Influence: Stringent regulations on biological material handling are shaping compliance and operational practices. Additionally, increased investment in research by biopharmaceutical firms is fueling demand for reliable biopreservation solutions.
Segmentation Analysis
- By Product Analysis: In 2023, the equipment segment led the biopreservation market with a 44.4% share. This growth was driven by innovations in cryopreservation systems, freezers, and refrigerators that maintain biological sample integrity. Rising demand from cell and gene therapy research, combined with the adoption of automated systems and LIMS integration, is enhancing sample management. Government funding and the expansion of biobanks and research facilities are further accelerating demand for advanced preservation equipment.
- By Application Analysis: The biobanking segment accounted for 50.0% of the market in 2023. This dominance stems from increased demand for long-term storage of biological samples to support research, diagnostics, and personalized medicine. With rising chronic disease rates, biobanks are essential in genomic studies, drug development, and biomarker research. Government programs, pharma collaborations, and technological advances in cryogenic storage and automation continue to support the segment’s expansion, particularly across emerging markets.
- By Cell Provider Analysis: In 2023, tumor cells held a 38.5% revenue share due to growing emphasis on cancer research and precision oncology. These cells are vital for drug testing, targeted therapy development, and genomics studies. Global cancer prevalence and the rise of immunotherapies and cell-based treatments are increasing demand for preserved tumor cells. Academic-industry collaborations and public funding are strengthening this segment, while improved preservation methods ensure long-term viability and research utility.
Market Segments
By Product
- Equipment
- Freezers
- Refrigerators
- Consumables
- Vials
- Straws
- Microtiter
- Bags
- Liquid Nitrogen
- Media
- Pre-formulated
- Home-brew
- Laboratory Information Management System [LIMS]
By Application
- Regenerative Medicine
- Cell Therapy
- Gene Therapy
- Others
- Biobanking
- Human Eggs
- Human Sperm
- Veterinary IVF
- Drug Discovery
By Cell Provider
- CD34+
- CD19+
- MSC
- iPSC
- hESC
- Tumor Cells
- Others
Regional Analysis
North America Maintains Leadership in the Biopreservation Market
In 2023, North America held the largest revenue share of 42.2% in the global biopreservation market. This dominance is attributed to the region’s advanced infrastructure in biobanking, regenerative medicine, and personalized healthcare. The increasing demand for organ transplants, cell therapies, and vaccine storage has driven the adoption of cryopreservation and hypothermic storage technologies.
Key industry players continue to secure substantial investments to expand their offerings. Notably, in November 2023, BioLife Solutions raised USD 10.4 million through a private placement by Casdin Capital. The funding has enabled the company to scale its operations and enhance its biopreservation media portfolio. Ongoing innovation, along with intensive research activities in the biotechnology and pharmaceutical sectors, continues to support regional market growth.
Asia Pacific to Register the Fastest Growth Rate
The Asia Pacific region is projected to experience the highest CAGR during the forecast period, driven by increased investments in biopharmaceutical infrastructure and rising demand for cell-based therapies. Countries such as China, Japan, and South Korea are emerging as regional leaders in biopreservation.
In 2024, Merck announced a major investment of over USD 321.7 million to establish a Bioprocessing Production Center in Daejeon, South Korea—the largest investment by its Life Science business in Asia Pacific. This facility will support advanced bioprocessing technologies and is expected to generate around 300 new jobs by 2028. Expanding regenerative medicine initiatives and biobanking activities are expected to further drive market growth across the region.
Emerging Trends
- Use of Lactic Acid Bacteria (LAB): Lactic Acid Bacteria are commonly used in biopreservation due to their ability to produce substances like bacteriocins, which inhibit harmful bacteria. These bacteria are not only effective in preserving food but also enhance its taste and nutritional value.
- Application of Bacteriocins: Bacteriocins are natural antimicrobial peptides produced by LAB. They are effective against foodborne pathogens such as Listeria monocytogenes and Staphylococcus aureus. Their use in food preservation helps in extending shelf life and ensuring safety.
- Integration with Advanced Analytical Methods: Modern analytical techniques are being employed to better understand and optimize biopreservation processes. This includes studying the genetic and molecular mechanisms of antimicrobial activity, leading to more targeted and efficient preservation strategies.
Use Cases
Food Industry
- Dairy Products: Incorporating LAB in cheese and yogurt production helps prevent spoilage and pathogenic bacterial growth.
- Meat Products: Applying bacteriocins can reduce the risk of contamination by harmful bacteria, thereby extending shelf life.
- Vegetables and Fruits: Using natural preservatives helps maintain freshness and reduce spoilage during storage and transportation.
Healthcare Sector
- Preserving Biological Samples: Ensuring the longevity and integrity of blood, tissues, and other biological specimens for research and diagnostic purposes.
- Probiotic Development: Enhancing the stability and efficacy of probiotic formulations used for gut health.
Agriculture
- Seed Preservation: Maintaining seed viability during storage.
- Post-Harvest Protection: Reducing spoilage of crops after harvest through natural antimicrobial agents.
Conclusion
In conclusion, biopreservation is essential for maintaining the viability of biological materials used in healthcare, biotechnology, and research. Its application spans regenerative medicine, organ transplantation, biobanking, and food safety. The global market is witnessing robust growth, fueled by advancements in cryopreservation technologies, increased demand for personalized medicine, and expanded research initiatives.
North America currently leads the market, while Asia Pacific is projected to grow the fastest due to strategic investments and infrastructure development. Emerging trends such as the use of LAB and bacteriocins are enhancing preservation methods. Overall, biopreservation remains a cornerstone of innovation in modern life sciences.
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