Gamma Knife Radiosurgery Market to Surpass USD 742.3 Million By 2033

Trishita Deb
Trishita Deb

Updated · Apr 3, 2025

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Overview

New York, NY – April 03, 2025 – Global Gamma Knife Market size is expected to be worth around USD 742.3 Million by 2033 from USD 470.3 Million in 2023, growing at a CAGR of 5.2% during the forecast period from 2024 to 2033.

Gamma Knife Radiosurgery, a cutting-edge, non-invasive treatment, is revolutionizing the field of neurosurgery. Unlike traditional brain surgery, this advanced technique delivers highly focused radiation to treat brain tumors, vascular malformations, and neurological disorders with extreme precision.

Gamma Knife technology utilizes multiple beams of radiation that converge on a targeted area, minimizing damage to surrounding healthy tissue. The procedure is typically performed on an outpatient basis, reducing hospital stays and recovery time. Patients experience minimal discomfort, as no incisions are required.

This breakthrough treatment is widely recognized for its effectiveness in treating conditions such as brain metastases, arteriovenous malformations (AVMs), trigeminal neuralgia, and certain types of benign and malignant brain tumors. With its high success rate and reduced side effects compared to conventional surgery, Gamma Knife Radiosurgery is becoming the preferred option for many patients and healthcare providers.

Medical institutions worldwide are adopting this state-of-the-art technology, further enhancing the accessibility of precision-based neurosurgical treatments. As advancements in radiosurgery continue, Gamma Knife remains at the forefront of non-invasive brain treatments, offering hope to patients seeking safer and more effective medical solutions.

Gamma Knife Market Size Forecast

Key Takeaways

  • The Gamma Knife market is expected to reach USD 742.3 million by 2033.
  • In 2023, the market was valued at USD 470.3 million.
  • The market is projected to grow at a CAGR of 5.2% from 2023 to 2033.
  • Malignant tumors held a dominant market share of over 46.2% in 2023.
  • Hospitals accounted for over 43% of the market share in 2023.
  • Asia-Pacific (APAC) led the market with a 38.5% share in 2023.
  • India’s market is growing at a CAGR of 11.2% through 2033, driven by medical tourism and government initiatives.
  • China’s market is expected to expand at a CAGR of 10% through 2033, supported by increased healthcare spending.
  • Elekta AB dominates the market with a share of over 50%, followed by Varian Medical Systems Inc. with approximately 30%.

Segmentation Analysis

Indications Analysis: In 2023, malignant tumors dominated the Gamma Knife market with over a 46.2% share, driven by the rising prevalence of cancerous brain tumors and demand for precise, non-invasive treatments. Benign tumors are also a key segment, benefiting from Gamma Knife’s targeted approach with minimal side effects. Vascular disorders, including arteriovenous malformations, rely on Gamma Knife’s precision, boosting its adoption. Functional disorders like trigeminal neuralgia contribute to market growth due to its painless treatment. Ocular diseases are an emerging segment, gaining traction for non-invasive eye treatments.

End-Use Analysis: Hospitals led the Gamma Knife market in 2023 with over a 43% share, driven by their ability to manage complex procedures and provide comprehensive care. Clinics are growing as they offer specialized, efficient Gamma Knife treatments, especially in urban areas. Ambulatory Surgery Centers (ASCs) are expanding due to their cost-effectiveness and convenience, attracting patients seeking outpatient procedures. Their role in the market is increasing as technology advancements enhance treatment accessibility.

Market Segments

Based on Indication

  • Malignant tumors
  • Benign tumors
  • Vascular disorders
  • Functional disorders
  • Ocular diseases
  • Other Indications

Based on Anatomy

  • Head
  • Neck
  • Other Body Parts

Based on End-Use

  • Hospital
  • Clinics
  • Ambulatory Surgery Centers

Regional Analysis

In 2023, Asia-Pacific (APAC) led the Gamma Knife market with a 38.5% share, valued at USD 172.5 million. This dominance is driven by the increasing prevalence of neurological disorders, higher healthcare investments, and improved accessibility to Gamma Knife surgeries. These factors are expected to sustain APAC’s market growth in the coming years.

North America, particularly the United States, is witnessing rising adoption of Gamma Knife technology, supported by clinical studies exploring its applications in treating essential tremors, Parkinson’s disease, and glioblastoma. The expansion of Gamma Knife radiotherapy is projected to further drive market growth.

India and China are key growth markets. India’s Gamma Knife sector is growing at an 11.2% CAGR through 2033, fueled by its strong medical tourism industry and government initiatives to enhance healthcare infrastructure. Meanwhile, China’s market is expanding at a 10% CAGR, driven by increased healthcare spending, expanded insurance coverage, and a rising cancer incidence.

In Europe, Germany’s Gamma Knife market is expected to grow at a 4.1% CAGR through 2033, supported by a well-developed healthcare infrastructure and a rising burden of brain tumors and neurological disorders. Japan’s market, growing at approximately 7.5% CAGR, benefits from continuous technological advancements and collaborations between healthcare institutions and technology providers.

Overall, the Gamma Knife market is experiencing substantial growth across regions, driven by advancements in technology, increasing awareness of its benefits, and expanding applications in neurological and oncological treatments.

Emerging Trends

  • Shift Toward Linear Accelerator (LINAC) Systems: There is a gradual transition from Gamma Knife systems to LINAC-based technologies. This shift is attributed to LINAC’s versatility in treating various conditions and its adaptability to outpatient settings, enhancing patient convenience.
  • Technological Advancements: Innovations in imaging and treatment planning are enhancing the precision and effectiveness of GKRS. These advancements aim to improve patient outcomes and expand the range of treatable conditions.
  • Cost Dynamics: The high installation and maintenance costs of Gamma Knife units, particularly due to the use of radioactive cobalt, have been a concern. However, increased production of radioactive materials may potentially reduce these expenses, making GKRS more accessible.

Use Cases

  • Brain Metastases: GKRS is a primary treatment for brain metastases, offering over 90% tumor control rates in appropriately selected patients.
  • Trigeminal Neuralgia: For patients with trigeminal neuralgia, GKRS provides pain relief in approximately 90% of cases within one year post-treatment.
  • Arteriovenous Malformations (AVMs): GKRS achieves a 90% success rate in treating small AVMs (less than 3 cm), effectively reducing the risk of hemorrhage.
  • Meningiomas and Acoustic Neuromas: GKRS offers high tumor control rates for benign tumors like meningiomas and acoustic neuromas, preserving neurological function and minimizing complications.

Conclusion

The Gamma Knife market is experiencing significant growth, driven by rising demand for non-invasive neurosurgical treatments, technological advancements, and expanding applications in oncology and neurology. Asia-Pacific leads the market, with strong contributions from India and China, while North America and Europe continue to adopt Gamma Knife technology at a steady pace.

Despite high installation costs, increasing accessibility and advancements in treatment planning are enhancing market expansion. The emergence of LINAC-based alternatives and ongoing research into Gamma Knife’s effectiveness in various neurological conditions further support its long-term adoption. Overall, the Gamma Knife market remains a vital segment in precision-based radiosurgery.

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Trishita Deb

Trishita Deb

Trishita has more than 8+ years of experience in market research and consulting industry. She has worked in various domains including healthcare, consumer goods, and materials. Her expertise lies majorly in healthcare and has worked on more than 400 healthcare reports throughout her career.

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