Drug Repurposing Market to Reach USD 51.8 Billion by 2033, Growing at 4.5% CAGR

Trishita Deb
Trishita Deb

Updated · Oct 10, 2025

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Overview

New York, NY – Oct 10, 2025 – The Global Drug Repurposing Market size is expected to be worth around USD 51.8 Billion by 2033 from USD 33.7 Billion in 2024, growing at a CAGR of 4.5% during the forecast period from 2025 to 2033.

Drug repurposing, also known as drug repositioning, has emerged as a cost-effective and time-efficient approach in modern healthcare. Instead of developing entirely new compounds, this strategy identifies new therapeutic uses for existing or previously approved drugs. The process significantly reduces research timelines, lowers development costs, and enhances the probability of clinical success, since the safety profiles of these drugs are already well-documented.

The growing global focus on drug repurposing is driven by rising healthcare demands, high costs associated with traditional drug discovery, and the urgent need for treatments for rare and emerging diseases. By leveraging computational biology, artificial intelligence, and big data analytics, pharmaceutical companies and research institutions are accelerating the identification of novel drug-disease associations.

Several successful examples have demonstrated the potential of this approach. Drugs initially designed for conditions such as hypertension, depression, or viral infections have been successfully repurposed to treat cancer, neurological disorders, and even COVID-19. These achievements highlight drug repurposing as a transformative force in advancing personalized medicine and broadening treatment accessibility.

With increasing collaborations between academia, industry, and government bodies, drug repurposing is expected to reshape the pharmaceutical landscape. By unlocking new applications for existing drugs, this strategy offers hope for faster, safer, and more affordable treatments to address unmet medical needs globally.

Drug Repurposing Market Size

Key Takeaways

  • Market Size: The Global Drug Repurposing Market size is expected to be worth around USD 51.8 Billion by 2033 from USD 33.7 Billion in 2024.
  • Market Growth: The market is anticipated to expand at a compound annual growth rate (CAGR) of 4.5% during the forecast period, 2025–2033.
  • Type of Approach: The disease-centric approach accounted for the largest share, representing 42.6% of the market in 2023.
  • Therapeutic Area: Repurposing within the same therapeutic area held a dominant position with 67.3% market share in 2023, a trend expected to strengthen further in the coming years.
  • Drug Molecules: Biologics emerged as the leading category, contributing to 61.5% of the overall market share.
  • Regional Analysis: North America led the global market, generating revenues of USD 14.8 billion in 2023 and capturing a 46.3% share.
  • Strategic Approaches: Market participants are focusing on product innovation, geographical expansion, mergers, and acquisitions to address increasing demand and strengthen their competitive positioning.
  • Pandemic Influence: The market demonstrated resilience during the pandemic, supported by the increased recommendation of supplements and repurposed drugs by healthcare providers worldwide.

Regional Analysis

The global drug repurposing market demonstrates significant geographical diversity, spanning North America, Europe, Latin America, and the Middle East & Africa. Among these, North America emerged as the leading region in 2023, capturing 46.3% of the market share and generating revenues of USD 14.8 billion. In contrast, the Asia Pacific market is projected to witness remarkable expansion, supported by a substantial Compound Annual Growth Rate (CAGR) during the forecast period.

The dominance of North America is primarily attributed to intensified research and development activities directed toward the repurposing of existing drugs. These initiatives are driving innovation and ensuring the region’s strong position in the global market.

Additionally, the COVID-19 pandemic further reinforced the relevance of drug repurposing, as healthcare providers across the globe increasingly recommended repurposed drugs and nutritional supplements to address urgent medical needs. This trend has underscored the strategic importance of repurposing approaches and is expected to sustain the market’s resilience in the coming years.

Frequently Asked Questions on Drug Repurposing

  • What is drug repurposing?
    Drug repurposing is the process of identifying new therapeutic uses for existing or previously approved drugs. This approach reduces development timelines, lowers costs, and leverages known safety profiles to accelerate the availability of treatments for various diseases.
  • Why is drug repurposing important?
    Drug repurposing is important because it offers a faster, safer, and more cost-effective pathway to drug development. By reusing approved drugs, pharmaceutical companies can address unmet medical needs and expand treatment options for rare, emerging, or complex diseases.
  • What are examples of successful drug repurposing?
    Several drugs initially designed for conditions like hypertension, depression, or viral infections have been successfully repurposed. For instance, some antiviral drugs were redirected to treat COVID-19, while cancer therapies have been adapted from cardiovascular or neurological drug candidates.
  • How does drug repurposing benefit patients?
    Patients benefit from drug repurposing through earlier access to affordable therapies with proven safety. Since the risk of adverse effects is already known, treatments can move quickly through clinical trials, ensuring improved healthcare outcomes with reduced uncertainty.
  • What role does technology play in drug repurposing?
    Technologies such as artificial intelligence, big data analytics, and computational biology enhance drug repurposing. These tools allow researchers to identify new drug-disease associations, streamline discovery processes, and increase accuracy in predicting potential therapeutic applications for existing compounds.
  • Which approach dominates the drug repurposing market?
    The disease-centric approach dominated the market in 2023, accounting for 42.6% of the total share. This method focuses on existing drugs for specific diseases, making it one of the most widely adopted strategies in repurposing practices.
  • Which therapeutic area leads in drug repurposing?
    Repurposing within the same therapeutic area held the highest share of 67.3% in 2023. This dominance is expected to continue, as it allows pharmaceutical companies to expand indications of existing drugs within already established treatment categories.
  • What type of drug molecules are most prevalent in the market?
    Biologics accounted for a substantial 61.5% market share in 2023. Their complexity, efficacy, and adaptability make them central to repurposing initiatives, offering wide-ranging applications across oncology, immunology, and infectious disease treatments.
  • Which region dominates the drug repurposing market?
    North America dominated the global market in 2023, generating USD 14.8 billion in revenue with a 46.3% share. The region’s leadership is attributed to strong research and development efforts, advanced healthcare infrastructure, and extensive adoption of repurposed therapies.

Conclusion

The global drug repurposing market is positioned for steady growth, driven by rising healthcare needs, high costs of traditional drug discovery, and increasing reliance on advanced technologies. North America continues to dominate, supported by strong research and development, while Asia Pacific shows promising growth potential. The dominance of biologics, same therapeutic area repurposing, and disease-centric approaches highlights the market’s evolving structure.

Furthermore, the resilience demonstrated during the pandemic underscores its critical importance in addressing urgent medical challenges. Moving forward, continued collaborations and strategic initiatives will reinforce drug repurposing as a transformative force in global healthcare innovation.

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Trishita Deb

Trishita Deb

Trishita has more than 8+ years of experience in market research and consulting industry. She has worked in various domains including healthcare, consumer goods, and materials. Her expertise lies majorly in healthcare and has worked on more than 400 healthcare reports throughout her career.

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