Ozempic Market To Hit USD 24 Billion by 2034, Growing at 8.2% CAGR

Trishita Deb
Trishita Deb

Updated · Jun 5, 2025

SHARE:

Market.us Media, we strive to bring you the most accurate and up-to-date information by utilizing a variety of resources, including paid and free sources, primary research, and phone interviews. Learn more.
close
Advertiser Disclosure

At Market.us Media, we strive to bring you the most accurate and up-to-date information by utilizing a variety of resources, including paid and free sources, primary research, and phone interviews. Our data is available to the public free of charge, and we encourage you to use it to inform your personal or business decisions. If you choose to republish our data on your own website, we simply ask that you provide a proper citation or link back to the respective page on Market.us Media. We appreciate your support and look forward to continuing to provide valuable insights for our audience.

Overview

New York, NY – June 05, 2025 – Global Ozempic Market size is expected to be worth around US$ 24.0 billion by 2034 from US$ 8.2% billion in 2024, growing at a CAGR of 8.2% during the forecast period 2025 to 2034.

Novo Nordisk A/S announces ongoing success with its GLP-1 receptor agonist, Ozempic (semaglutide), in improving glycemic control and promoting weight loss among adults with type 2 diabetes. Approved by the U.S. Food and Drug Administration (FDA), Ozempic is administered once weekly and has shown significant efficacy in reducing HbA1c levels and aiding weight management when combined with diet and exercise.

Clinical studies, including the SUSTAIN trial series, have demonstrated a reduction in HbA1c by up to 1.5% and weight loss of up to 14 pounds over 30–56 weeks. Ozempic continues to play a critical role in diabetes care, with additional cardiovascular benefits. According to the American Diabetes Association (ADA), cardiovascular risk reduction is a priority in treatment plans for patients with type 2 diabetes.

Novo Nordisk remains committed to ensuring global access through expanded production and strategic partnerships. The company is also investing in further research for potential benefits in obesity management and metabolic disorders. As type 2 diabetes prevalence continues to rise worldwide, effective, long-term treatments such as Ozempic are essential in reducing the burden of chronic disease. Healthcare providers are encouraged to consider semaglutide-based therapies as part of a comprehensive approach to diabetes care.

Global Ozempic Market Size

Key Takeaways

  • In 2024, Ozempic generated revenue of approximately US$ 8.2 billion, with a compound annual growth rate (CAGR) of 8.2%, and is projected to reach US$ 24.0 billion by 2033.
  • Based on route of administration, the market is segmented into oral and parenteral forms, with the oral segment dominating in 2023, accounting for 58.7% of the market share.
  • By distribution channel, the market is categorized into hospital pharmacies, retail pharmacies, and online pharmacies. Among these, hospital pharmacies held the largest share at 46.8%.
  • North America emerged as the leading regional market, capturing a 42.3% share in 2023, driven by high adoption rates and advanced healthcare infrastructure.

Segmentation Analysis

  • Route of Administration Analysis: In 2023, the oral segment accounted for 58.7% of the market share, driven by the rising preference for non-invasive, easy-to-use treatment options. Oral administration enhances patient compliance compared to injectables, supporting long-term diabetes management. Increased awareness of the benefits of oral semaglutide and ongoing innovations in drug delivery technologies are expected to improve efficacy and reliability. This trend aligns with the broader movement toward patient-centric healthcare and is anticipated to support sustained segment growth.
  • Distribution Channel Analysis: Hospital pharmacies held a dominant 46.8% market share due to their central role in diabetes care and chronic disease management. The increasing burden of type 2 diabetes has led to greater demand for reliable treatment options like Ozempic. Hospitals are expanding access to such medications to improve patient outcomes. Collaborations between pharmaceutical companies and hospital networks are further strengthening distribution channels, ensuring consistent supply and timely access for patients requiring advanced glucose-lowering therapies.

Market Segments

Route of Administration

  • Oral
  • Parenteral

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Regional Analysis

North America held the largest share of the Ozempic market in 2023, accounting for 42.3% of total revenue. This dominance is attributed to the high prevalence of type 2 diabetes and increased awareness of GLP-1 receptor agonists for effective glycemic control and weight management.

According to the CDC’s National Diabetes Statistics Report 2022, over 130 million U.S. adults live with diabetes or prediabetes. Widespread adoption of Ozempic among both diabetic and overweight individuals has been driven by its dual benefits, growing physician confidence, and patient awareness supported by direct-to-consumer marketing. Improved insurance coverage and favorable reimbursement policies have further contributed to accessibility.

In contrast, the Asia Pacific region is expected to witness the highest CAGR during the forecast period. Rising diabetes prevalence due to rapid urbanization, sedentary lifestyles, and dietary changes in countries like India, China, and Japan is fueling demand for advanced treatments.

Government-led diabetes awareness campaigns, expanded insurance access, and telemedicine integration are enhancing care delivery. Collaborations between pharmaceutical firms and local healthcare providers are improving availability and affordability, while increasing middle-class income levels support wider adoption of Ozempic across the region.

Emerging Trends

The prescribing of Ozempic has been expanding rapidly in recent years. Between 2019 and 2023, Medicare Part D enrollees filled approximately 523,225 prescriptions in 2019, rising to 6,933,461 in 2023, representing a 1,225 percent increase in annual prescriptions. Over the same period, spending under Medicare Part D on Ozempic alone grew from roughly $2.6 billion in 2021 to $4.6 billion in 2022, accounting for about 2 percent of the total $240 billion Part D drug spend in 2022. This rapid growth has prompted selection of Ozempic for Medicare’s second cycle of drug price negotiations, with $14.4 billion in gross covered costs and 2.29 million enrollees identified for November 2023–October 2024.

Multiple clinical trials are investigating new therapeutic areas for semaglutide beyond type 2 diabetes. Semaglutide (the active ingredient in Ozempic) is being tested for reducing alcohol intake in patients with alcohol use disorder and obesity, as well as in early Alzheimer’s disease with results expected by 2025. Cardiovascular disease trials are ongoing, including SELECT for obesity patients at high cardiovascular risk, in which 17,604 participants were enrolled (8,803 received semaglutide; 8,801 received placebo), demonstrating a reduction in primary cardiovascular events from 8.0 percent in placebo to 6.5 percent with semaglutide (hazard ratio 0.80; 95 percent CI 0.72–0.90; P < 0.001) over a mean follow-up of 39.8 months. Trials for chronic kidney disease, nonalcoholic steatohepatitis (NASH), idiopathic intracranial hypertension, and obstructive sleep apnea are also in progress).

Combination therapies involving semaglutide have demonstrated enhanced efficacy. In December 2024, Novo Nordisk’s REDEFINE 1 trial compared weekly cagrilintide 2.4 mg plus semaglutide 2.4 mg (CagriSema) versus semaglutide alone and placebo in adults with obesity or overweight and comorbidities. Participants treated with CagriSema lost an average of 20.4 percent of body weight over 68 weeks, compared to 14.9 percent with semaglutide alone and 3.0 percent with placebo. A subsequent REDEFINE 2 trial reported that overweight or obese adults with type 2 diabetes lost 15.7 percent of body weight when treated with the combination, compared to 3.1 percent with placebo over 68 weeks. These results suggest that next-generation regimens may shift prescribing patterns toward combination GLP-1–based therapies.

Patent expirations and pricing pressures are reshaping access to Ozempic. In the United States, the semaglutide patent is expected to expire in December 2031, while in China and Brazil, all semaglutide patents were declared invalid or scheduled to expire in 2026. In response to escalating Medicare Part D spending—tripling from $1.5 billion in 2020 to $4.6 billion in 2022—Medicare began preparing price negotiations under the Inflation Reduction Act. Lower Medicare reimbursement rates are projected for Ozempic starting January 1, 2027, following successful negotiations in late 2024. Additionally, concerns about counterfeit Ozempic pens prompted FDA warnings in late 2023, highlighting the need for vigilance.

Use Cases

  • Type 2 Diabetes Management: Ozempic was approved by the U.S. FDA in December 2017 for improving glycemic control in adults with type 2 diabetes. In pivotal trials, 4,087 patients were enrolled across seven global studies to evaluate safety and efficacy. A separate cardiovascular outcomes trial included 3,297 patients at high cardiovascular risk in 20 countries, demonstrating significant reductions in glycated hemoglobin (HbAc) and favorable cardiovascular event rates for semaglutide-treated patients. Weekly semaglutide was associated with mean HbAc reductions of up to 1.5 percentage points compared to placebo, and 20–40 percent of patients achieved fasting plasma glucose levels below 130 mg/dL, depending on dose.
  • Obesity and Weight Management: Ozempic is widely used off-label for weight loss in adults with overweight or obesity. In a phase II trial published in NEJM, once-weekly semaglutide 2.4 mg plus lifestyle intervention led to an average weight reduction of 14 percent over 68 weeks, compared to placebo. In SELECT, adults without diabetes but with obesity and established cardiovascular disease exhibited a mean weight loss of 15–20 percent when treated with semaglutide 2.4 mg weekly, significantly reducing cardiovascular events (6.5 percent vs 8.0 percent placebo). These data have informed guideline updates, and as of mid-2025, approximately 3.5 million Medicare and 4 million Medicaid beneficiaries may qualify for coverage of GLP-1 weight-loss drugs like Ozempic under proposed HHS rules.
  • Cardiovascular Risk Reduction: Semaglutide has demonstrated cardiovascular benefits in overweight or obese adults with established disease. In the SELECT trial (NCT03574597), 17,604 patients were randomized (8,803 to semaglutide, 8,801 to placebo) and followed for a mean of 39.8 months. Semaglutide reduced the primary composite endpoint (death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke) from 8.0 percent in the placebo arm to 6.5 percent in the treatment arm (hazard ratio 0.80; 95 percent CI 0.72–0.90; P < 0.001). These findings have led to guideline considerations for semaglutide in reducing cardiovascular risk among obese adults with cardiovascular disease, independent of diabetes status.
  • Exploratory and Off-Label Indications: Ozempic is under investigation for multiple off-label uses. Semaglutide is being tested for alcohol use disorder in obese patients, with early trials indicating reductions in alcohol intake measured by drinks per week over 12 weeks. In Alzheimer’s disease, a phase III trial is evaluating cognitive outcomes in early Alzheimer’s patients receiving semaglutide, with readouts anticipated by late 2025. Trials in chronic kidney disease aim to assess glomerular filtration rate decline over 104 weeks. Additionally, semaglutide’s role in nonalcoholic steatohepatitis is being quantified by histologic improvement scores, with interim data showing a ≥2-point NAFLD activity score reduction in 45 percent of treated patients versus 20 percent with placebo. These emerging use cases underscore the expanding therapeutic scope of Ozempic within metabolic and organ-specific indications.

Conclusion

Ozempic (semaglutide) continues to play a pivotal role in transforming the management of type 2 diabetes, obesity, and associated cardiovascular risks. Its growing global adoption is supported by robust clinical evidence, strong commercial performance, and expanding therapeutic applications. With promising outcomes in ongoing trials and rising demand across healthcare systems, Ozempic is positioned to remain a cornerstone in chronic disease management.

Anticipated patent expirations, regulatory actions, and combination therapies are expected to shape its future trajectory. As the global burden of metabolic disorders intensifies, Ozempic offers a clinically validated, multi-indication solution aligned with the evolving needs of patients and providers.

Discuss your needs with our analyst

Please share your requirements with more details so our analyst can check if they can solve your problem(s)

SHARE:
Trishita Deb

Trishita Deb

Trishita has more than 8+ years of experience in market research and consulting industry. She has worked in various domains including healthcare, consumer goods, and materials. Her expertise lies majorly in healthcare and has worked on more than 400 healthcare reports throughout her career.

Latest from the featured industries
Request a Sample Report
We'll get back to you as quickly as possible