Chromatography Market To Expand Steadily, Reaching US$ 15.9 Billion By 2034

Overview

New York, NY – May 29, 2025 – The Global Chromatography Market size is expected to be worth around US$ 15.9 billion by 2034 from US$ 9.6 billion in 2024, growing at a CAGR of 5.2% during the forecast period 2025 to 2034.

Chromatography, a critical analytical technique used to separate, identify, and quantify components in a mixture, continues to witness strong market growth across pharmaceutical, biotechnology, food safety, and environmental testing sectors. This method plays a central role in quality control, drug development, and forensic science due to its high sensitivity and accuracy.

The market’s expansion is being driven by the increasing demand for high-purity substances, rising adoption of chromatography in drug discovery and diagnostics, and growing emphasis on food and environmental safety standards. Technological advancements such as automated systems, miniaturized columns, and improved detectors have enhanced operational efficiency and data accuracy, enabling broader use in both research and industrial settings.

Governments and regulatory agencies globally are also supporting the adoption of advanced chromatography technologies to comply with strict analytical standards. Agencies like the U.S. FDA and European Medicines Agency require validated chromatographic methods for pharmaceutical product approval and quality assurance.

In the healthcare industry, chromatography is widely used for biomolecular analysis and therapeutic drug monitoring. Furthermore, the increasing number of academic research projects and clinical trials involving biologics is expected to contribute to sustained demand. With continuous innovation, the chromatography market is poised to maintain steady growth, reinforcing its role as an essential analytical tool across scientific disciplines and regulatory frameworks.

Key Takeaways

• In 2023, the global chromatography market recorded a revenue of approximately US$ 6 billion and is projected to grow at a CAGR of 5.2%, reaching around US$ 15.9 billion by 2033.
• Within the chromatography systems segment, the market is categorized into gas, liquid, fluid, and thin layer chromatography. Liquid chromatography held the leading position in 2023, accounting for 36.4% of the market share.
• Regarding chromatography accessories, the market is segmented into columns, pressure regulators, solvents, detectors, and others. Columns dominated the category, capturing 42.7% of the total share.
• In terms of end-users, the market includes academic & research institutes, pharmaceutical & biotechnology companies, food & beverage companies, life science industries, and others. The pharmaceutical & biotechnology sector emerged as the leading segment with a 41.2% revenue share.
• Regionally, North America led the chromatography market in 2023, contributing 40.3% of the total market share.

Segmentation Analysis

• Chromatography Systems Analysis: In 2023, the liquid chromatography segment led the market with a 36.4% share, driven by its critical role in chemical, pharmaceutical, and environmental testing. Its ability to deliver high-resolution separation makes it ideal for analyzing complex mixtures. Advancements in column technology and detector sensitivity are expected to support future growth. Increasing use in clinical diagnostics, food safety, and biotechnology will further enhance adoption, as industries demand precise analytical tools for quality control and regulatory compliance.
• Accessories Analysis: Columns accounted for 42.7% of the chromatography accessories market in 2023 due to their essential function in separation processes. Rising demand from pharmaceutical, biotech, and environmental sectors is boosting adoption. The trend toward specialized column typesfor proteins or environmental pollutants supports ongoing growth. Innovations in column design and packing materials are improving efficiency and precision, reinforcing their importance. As chromatographic applications become more specific, demand for high-performance, durable columns is projected to remain strong.
• End-user Analysis: Pharmaceutical and biotechnology companies dominated the end-user segment in 2023, contributing 41.2% of the total revenue. This dominance is attributed to chromatography’s role in drug development, impurity detection, and research. Demand is expected to rise with the focus on biologics, biosimilars, and personalized medicine. Strict regulatory standards are prompting greater investment in analytical tools. Additionally, expanding use in gene therapy, proteomics, and biomarker discovery is likely to strengthen this segment’s market position further.

Market Segments

Chromatography Systems

• Gas
• Liquid
• Fluid
• Thin Layer

Accessories

• Columns
• Pressure Regulators
• Solvents
• Detectors
• Others

End-user

• Academic & Research Institutes
• Pharmaceutical & Biotechnology Company
• Food & Beverage Company
• Life Science Industries
• Others

Regional Analysis

In 2023, North America held the largest share of the chromatography market, accounting for 40.3% of total revenue. This dominance was supported by growing demand across pharmaceuticals, biotechnology, environmental testing, and food quality control sectors. The region’s focus on precision medicine, stringent regulatory frameworks, and the need for accurate analytical tools continues to drive market growth. A notable development was PerkinElmer Inc.’s launch of the GC 2400 Platform in June 2022, offering integrated GC, headspace sampling, and GC/MS for enhanced lab workflows and precise results.

In contrast, the Asia Pacific region is projected to witness the highest CAGR during the forecast period. Rising adoption of chromatography in pharmaceuticals, biotechnology, and environmental testing is fueling growth. Countries like China, India, and Japan are driving demand due to expanding healthcare and research infrastructure. Increasing chronic diseases, demand for personalized treatments, and environmental monitoring requirements are pushing adoption. Government initiatives and rising R&D investments further support growth. As a result, Asia Pacific is expected to emerge as a vital growth hub for the chromatography market in the coming years.

Emerging Trends

• Broader Adoption of LC-MS Interfaces: Liquid chromatography–mass spectrometry (LC-MS) interfaces such as thermospray and particle beam have been widely accepted over the last 15 years, enhancing sensitivity and structural characterization in environmental and pharmaceutical analyses.
• Thermal Extraction GC-MS for Air Quality: Thermal extraction gas chromatography–mass spectrometry (TE/GC-MS) is emerging as a key tool for analyzing fine aerosols. Hundreds of organic constituents can now be speciated in a single run, supporting source apportionment in air monitoring.
• High-Thermal-Resistance Columns: The use of modern, high-thermal-resistance chromatographic columns is reducing column bleeding and improving signal-to-noise ratios. This trend is driving better sensitivity and reliability in trace-level analyses.
• Integration of Artificial Intelligence: Artificial intelligence methods are being explored to optimize chromatographic method development. AI has begun to assist in peak detection and method parameter tuning, promising faster and more robust analyses.

Use Cases

• Air Quality and Aerosol Research: TE/GC-MS has been applied to ambient fine aerosols, speciating hundreds of individual organic compounds. This supports chemical mass balance models for source apportionment in urban air studies.
• Drinking Water Safety: Gas chromatography methods are used to detect nitrosamines in water at low-ng/L concentrations. Such analyses ensure compliance with health guidelines for trace contaminants.
• Clinical Diagnostics: Chromatography is routinely used in clinical laboratories to diagnose inborn errors of metabolism, such as amino acid and organic acid disorders, enabling accurate and early detection.
• Metabolomics Research: The NIH Metabolomics Workbench employs chromatography-based methods across 239 analytical protocols to profile metabolites in biological samples, supporting large-scale biomarker discovery.

Conclusion

The global chromatography market is poised for steady growth, driven by its critical role in pharmaceuticals, biotechnology, environmental testing, and clinical diagnostics. With increasing demand for high-purity substances, regulatory compliance, and advanced analytical techniques, the market is expected to reach US$ 15.9 billion by 2034.

Innovations in column design, AI integration, and LC-MS/GC-MS interfaces are enhancing precision and efficiency. North America leads in market share, while Asia Pacific is projected to grow fastest. As research intensifies and technology evolves, chromatography will remain indispensable for quality control, drug development, and scientific advancement across diverse industries.