Enzyme-linked immunosorbent assay (ELISA) is a biochemical technique used to detect antigens or antibodies in a sample. The ELISA is a diagnostic tool and is used in plant pathology, medicine, and food industry. It is a simple and quick procedure to identify antibodies, antigens, hormones, proteins, and peptides in biological samples. Antigens are those substances which stimulate the immune system in order to produce antibodies. The antibodies, also known as immunoglobulins are proteins that fight against foreign substances known as antigens.
Increasing prevalence of infectious diseases such as HIV, cancer, and others that are caused by viral, bacterial, mycotic, and parasitic organisms is a factor augmenting demand for enzyme-linked immunosorbent assay owing to its high sensitivity. ELISA is used to diagnose non-infectious diseases such as drugs, hormones, serum components, auto-immune diseases, and oncofetal proteins. Increasing R&D investments by government in healthcare sector in developing countries, and growing population, coupled with high disposable income are factors proliferating demand for enzyme-linked immunosorbent assay.
Availability of alternate immunoassays test and lack of affordability and accessibility of diagnostic tests in emerging countries are factors challenging growth of the global market. Development of automated platforms to run ELISA and launch of innovative products owing to improve performance, flexibility, sensitivity, productivity, and cost-effective technology are factors creating new opportunities for players operating in the global market.
Enzyme-linked immunosorbent assay is of two types i.e., ELISA sets and ELISA kits. ELISA kits are used to detect molecules or performing ligand-binding assays whereas the ELISA sets are used to develop enzyme-linked immunosorbent assays (ELISA) for natural or recombinant cells in serum, plasma, and cell culture supernatants. The reagents used in ELISA sets are stored at proper storage conditions but need to be brought at room temperature before use.
- By Type
- By Region
- By Application
Enzyme-linked immunosorbent assay is used in various applications such as ELISA in HIV, ELISA in West Nile Virus, detecting antigens or antibodies and biodefense. It is used in diagnosis of HIV infection, pregnancy tests, and measurement of soluble receptors or cytokines in serum or cell supernatant.
The market is segmented on the basis of geography such as North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Increasing investments in R&D for immunology and medicine, increasing pharmaceutical and biotechnology industries, and presence of major players in countries are factors augmenting demand for enzyme-linked immunosorbent assay in North America region. Growing pharmaceutical industry, increasing geriatric population, coupled with high spending capacity has a positive impact on the enzyme-linked immunosorbent assay market in Europe. Increasing investments by government and development of healthcare sector especially for clinical diagnosis, and growing population, coupled with high disposable income in the Asia Pacific region are factors driving demand for enzyme-linked immunosorbent assay.
The worldwide market for enzyme-linked immunosorbent assay is expected to register significant CAGR of around 5.5 % over the next ten years and was valued at 1,594.9 Mn in 2018.
Some of the prominent players operating in the target market include R&D Systems, Thermo Fisher Scientific, Ortho Clinical Diagnostics, BD Biosciences, ZEUS Scientific, Bio-Rad Laboratories, ALPCO, Enzo Life Sciences, BioMérieux, EMD Millipore, BioLegend, LOEWE Biochemica and Shenzhen YHLO Biotech.