A new study has revealed that patients who are suffering from type 2 diabetes should focus on losing at least 15 percent or more of their body weight to manage their disease. The authors of the study have said that losing 15 percent or more of body weight can slow down the growth of type 2 diabetes and it can overturn many cases of the dreaded disease and lessen multiple complications. Experts have presented this strategy at the Annual Meeting of the European Association this week. The co-author of the study, Dr. Ildiko Lingvay has said that the findings of the study have shown that the majority of patients who do not have cardiovascular diseases should focus on the main underlying driver of type 2 diabetes, that is obesity. Experts have said that obesity is the key abnormality that leads to a diagnosis of type 2 diabetes. Dr. Ildiko Lingvay is a researcher at the University of Texas Southwestern Medical Center. Dr. Ildiko Lingvay has said that the strategy will not just address type 2 diabetes and high blood pressure but it as well will reduce other complications linked to obesity. Losing at least 15 percent of body weight will reduce issues such as osteoarthritis, increased blood fats profile, fatty liver, obstructive sleep apnea, and hypertension as well, said the experts. Dr. Ildiko Lingvay has said that the approach mentioned in the study will have a positive impact on patients’ overall health. Dr. Priya Sumithran from the University of Melbourne, who is one of the co-authors of the study, has said that treatment of obesity to seek a sustained weight loss of 15 percent of body weight can effectively reduce the growth of type 2 diabetes and reverse the impact of the disease among some patients. The findings of the paper have been released in a journal called the Lancet.
Many studies have shown the benefits of weight loss in type 2 diabetes management. A direct trial where experts have tested intensive lifestyle intervention in patients who have been dealing with obesity and type 2 diabetes has shown a reduction in type 2 diabetes at 2 years in 70 percent of patients who have lost 15 Kgs of their body weight with a median baseline of 100 kg. Experts have said that many studies on obesity surgery as well have shown instant and lasting benefits among patients who are suffering from type 2 diabetes and obesity. The authors of the study have said that bariatric surgery or obesity can cut down the need for glucose-reducing drugs. Bariatric surgery will elevate multiple indicators for health in the long term. The authors of the study have mentioned a wide range of medicines that can help in weight management. Experts have said that five compounds such as orlistat, phentermine-topiramate, naltrexone-bupropion, liraglutide 3*0 mg, and semaglutide 2*4 mg have been authorized by one or more drug regulatory authorities across the world for severe weight management. In June 2021, the US Food and Drug Administration (FDA) has given approval to weekly semaglutide. Scientists are coming up with many other drugs such as tirzepatide and gastric inhibitory polypeptide for sustained weight loss. Studies of these newly developed drugs have shown that nearly 25 percent of patients who are dealing with type 2 diabetes can easily lose 15 percent of their body weight. The studies of these drugs have shown that the drugs can easily stabilize blood sugar in most participants. The authors of the new study have said that most patients who are suffering from type 2 diabetes are more likely to be insulin resistant that means the disease is probably triggered by body fat. Dr. Ildiko Lingvay has said that the presence of central adiposity, bigger waist size, skin tags, fatty liver disease, and hypertension are key indicators of body fat being the trigger of type 2 diabetes.
Dr. Lingvay has said that he has opposed a treatment to lose at least 15 percent of body weight, as it is the most efficient way to disturb the core pathophysiology of the disease. Therefore, such a treatment can change the curse of the disease in long term as well. Expert has said that such a treatment can prevent other metabolic issues that are linked to type 2 diabetes and obesity. The authors of the study have said that officials should include sustained weight loss as prime care in the treatment guidelines for patients with type 2 diabetes or T2D. Health officials should focus on the benefits of reducing obesity that will ultimately prevent T2D, said the experts. The US government has been investing a lot of money in treating patients with progressing T2D. There is a wide range of complications that come along with the disease. These complications along with disease can be addressed with sustained weight loss. Health care providers who are treating patients with T2D as well should focus on weight management. They should be trained in obesity management.